反应详情

100 g of manganese dioxide were added to 21 g of 2-propyl-5-thiazole-methanol in 1000 ml of benzene and the mixture was stirred for 3 hours at room temperature. 40 g of manganese dioxide were added and the mixture was stirred at room temperature for 2 hours after which another 20 g of managanese dioxide was added. The mixture was stirred for 16 hours at room temperature and was filtered and the filter was washed with methylene chloride. The filtrate was evaporated to dryness under reduced pressure to obtain 18.5 g of 2-propyl-5-thiazolecarboxaldehyde.

1. additionwas added
2. stirringThe mixture was stirred for 16 hours at room temperature
3. filtrationwas filtered
4. washthe filter was washed with methylene chloride
5. customThe filtrate was evaporated to dryness under reduced pressure