4-Methoxyphenylacetyl chloride → HCID 20370079, compound

HRID 616411Notes

Reaction equation

HRID 616411 reaction equation
COC1C=CC(CC(Cl)=O)=CC=1.[CH3:13][O:14][C:15]1[CH:20]=[CH:19][C:18]([CH:21]=[C:22]=[C:23]([CH3:29])[C:24]([O:26]CC)=[O:25])=[CH:17][CH:16]=1>>[CH3:13][O:14][C:15]1[CH:16]=[CH:17][C:18]([CH:21]=[C:22]=[C:23]([CH3:29])[C:24]([OH:26])=[O:25])=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 27346884-Methoxyphenylacetyl chlorideHCID 11253262HCID 11253262, compound

Product 1

HCID 20370079HCID 20370079, compound

Procedure

Repeating the procedure of Example 1 but replacing the p-thiomethylphenyl acetyl chloride with an equivalent amount of p-methoxyphenyl acetyl chloride, there is similarly obtained ethyl 4-(p-methoxyphenyl)-2-methyl-buta-2,3-dienoate, which when treated according to the procedure of Example 2, yields 4-(p-methoxyphenyl)-2-methyl-buta-2,3-dienoic acid (m.p. 105° - 108°, from ether/pentane).

Workup

  1. additiontreated

Sources & evidence

ORD record
ord-0172f85cc860490fad1bd1dbce7de11b
Source dataset
uspto-grants-1978_02
Patent number
US04073936

Reaction notes

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