Oxalic Acid → HCID 20370248, compound

HRID 616439Notes

Reaction equation

HRID 616439 reaction equation
[CH3:1][N:2]([CH2:4][CH:5]1[CH2:9][N:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[NH:7][C:6]1=[O:16])[CH3:3].[C:17]([OH:22])(=[O:21])[C:18]([OH:20])=[O:19]>CC(C)=O>[C:17]([OH:22])(=[O:21])[C:18]([OH:20])=[O:19].[CH3:3][N:2]([CH2:4][CH:5]1[CH2:9][N:8]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)[NH:7][C:6]1=[O:16])[CH3:1]

Participants

4

Reactant 2

HCID 971Oxalic AcidHCID 20370249HCID 20370249, compound

Product 1

HCID 20370248HCID 20370248, compoundYield 73%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The hydrogen oxalate salt was prepared by mixing the pyrazolidinone and oxalic acid in acetone solution. This gave a white solid which was recrystallised from ethanol to give colourless crystals of 4-dimethylaminomethyl-1-phenylpyrazolidin-3-one hydrogen oxalate (73% melting point 128°-9° C).

Workup

  1. customThis gave a white solid which
  2. customwas recrystallised from ethanol

Sources & evidence

ORD record
ord-8492b285cffb4a8689131d8f21d45237
Source dataset
uspto-grants-1978_02
Patent number
US04074051

Reaction notes

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