反应详情

To sixteen grams (0.1 mole) of ethylene glycol monobenzoate containing 20 gms (0.25 mole) of pyridine was added 22 gms (0.1 mole) of lauroyl chloride with stirring. With the final addition of lauroyl chloride approximately 50 ml of benzene was added and the mixture stirred for 1 hour. The pyridine hydrochloride was filtered off and the product water washed to remove residual pyridine. The benzene solution was dried over anhydrous sodium sulfate and percolated through a column filled with activated alumina to removal residual free acid. The solvent was removed at reduced pressure. The product, 2-benzoyloxyethyl laurate, was characterized on the basis of the chemical shifts in the NMR spectrum and the absence of OH-stretching and other bands associated with reaction byproducts or impurities.

1. additionwas added
2. stirringthe mixture stirred for 1 hour
3. filtrationThe pyridine hydrochloride was filtered off
4. washthe product water washed
5. customto remove residual pyridine
6. dry with materialThe benzene solution was dried over anhydrous sodium sulfate
7. additionfilled with activated alumina to removal residual free acid
8. customThe solvent was removed at reduced pressure
9. customother bands associated with reaction byproducts or impurities