3,4-Dichlorophenyl isocyanate → HCID 20367537, compound

HRID 616488Notes

Reaction equation

HRID 616488 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]=[C:10]=[O:11])[CH:5]=[CH:6][C:7]=1[Cl:8].[O:12]1[CH2:17][CH2:16][N:15]([CH:18]=[C:19]([CH3:21])[CH3:20])[CH2:14][CH2:13]1>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[CH:18]([N:15]3[CH2:16][CH2:17][O:12][CH2:13][CH2:14]3)[C:19]([CH3:21])([CH3:20])[C:10]2=[O:11])[CH:5]=[CH:6][C:7]=1[Cl:8]

Participants

3

Reactant 2

HCID 76073,4-Dichlorophenyl isocyanateHCID 102255Morpholine, 4-(2-methyl-1-propenyl)-

Product 1

HCID 20367537HCID 20367537, compound

Procedure

A 1.88 g. portion of 3,4-dichlorophenylisocyanate was added to 2.82 g. of 1-morpholino-1-isobutene. The mixture was stirred at room temperature for 48 hours. At the end of that time, the excess enamine was removed under vacuum, and the remaining oil, 3.0 g., was found by nuclear magnetic resonance analysis to be 1-(3,4-dichlorophenyl)-3,3-dimethyl-4-morpholino-2-azetidinone, a liquid.

Workup

  1. customAt the end of that time, the excess enamine was removed under vacuum

Sources & evidence

ORD record
ord-4ea1aaa506bc487389d6b9b9d87e7959
Source dataset
uspto-grants-1978_02
Patent number
US04075000

Reaction notes

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