反应详情

Two liters of ethanol were saturated with ammonia gas at 15°. At ambient temperature, 278.3 g of 2-cyano-3,3-bis(methylthio)propenenitrile were added portionwise. A sodium hydroxide trap was used to trap the methyl mercaptan by-product. After complete addition of the propenenitrile the reaction mixture was cooled to approximately 10°. The solid which separated was collected by filtration and washed with cold ethanol to give, after drying, 206.3 g of white 3-amino-2-cyano-3-(methylthio)propenenitrile, m.p. 228°-230°. The nmr was consistent with the assigned structure.

1. customA sodium hydroxide trap was used to trap
2. temperaturewas cooled to approximately 10°
3. customThe solid which separated
4. filtrationwas collected by filtration
5. washwashed with cold ethanol
6. customto give
7. customafter drying