Sulfuric Acid → HCID 13152888, compound

Participants

Reaction Steps

To 2-carbamoyl-6,11-dihydro-pyrrolo[2,1-b][3]-benzazepine-11-one (27 g., 0.112 moles) in 300 ml. of 50% sulfuric acid maintained at 50° C., was added slowly 25 g. of sodium nitrite in 75 ml. of water. At the end of the addition, the solid was filtered, washed with water and air-dried to yield 6,11-dihydro-11-oxo-pyrrolo[2,1-b][3]-benzazepine-2-carboxylic acid (24 g., 89%), m.p. 287°-290° C.

Provenance & Evidence