1-Bromododecane → 6-Dodecylthieno[2,3-c]pyridin-6-ium bromide

Participants

Reaction Steps

A mixture of thieno[2,3-c]pyridine (7 g; 0.052 mole), 1-bromododecane (13 g; 0.052 mole) and acetonitrile (100 cc) is refluxed during 4 hours. The solution is then concentrated in vacuo and the residue is triturated with ether to give, after filtration and drying, 12 g (Yield: 60%; m.p. = 95-100° C) 6-dodecyl-thieno[2,3-c]pyridinium bromide (derivative of the formula (IV)).

Provenance & Evidence