Hydrazine → Pyrazole, 3-phenyl-5-(o-tolyl)-

HRID 616724Notes

Reaction equation

HRID 616724 reaction equation
[C:1]1([C:7](=O)[CH2:8][C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[CH3:17])=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:19][NH2:20]>C(O)C>[C:1]1([C:7]2[CH:8]=[C:9]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=3[CH3:17])[NH:20][N:19]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 101986241,3-Propanedione, 1-(2-methylphenyl)-3-phenyl-

Product 1

HCID 2753068Pyrazole, 3-phenyl-5-(o-tolyl)-

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1-Phenyl-3-(o-tolyl)-1,3-propanedione (b.p. 170° C./0.01 mm Hg) is condensed with hydrazine in ethanol to give 3-phenyl-5-(o-tolyl)pyrazole, m.p. 112.5°-113.5° C.

Sources & evidence

ORD record
ord-f18881bea3464ab89f0a158378abcb73
Source dataset
uspto-grants-1978_02
Patent number
US04075342

Reaction notes

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