Methanethiol → HCID 86735489, compound

Participants

Reaction Steps

While passing in nitrogen and stirring, 3.1 g of methyl mercaptan are introduced into a suspension of 2.8 g of 55% sodium hydride in 150 ml of tetrahydrofurane and subsequently 18 g of N-(1'-methylthiocarbonylethyl)-N-chloroacetyl-2,6-dimethylaniline (prepared by chloroacetylating the intermediate obtained in Example 1a) with, for example, chloroacetyl chloride) in 50 ml of tetrahydrofurane were added dropwise. Stirring was continued for 48 hours at room temperature and the reaction mixture was diluted with 300 ml of diethyl ether, washed three times with water, dried over sodium sulphate and filtered. After recrystallisation from diethyl ether/petroleum ether, compound 2 had a melting point of 88°-92° C.

Provenance & Evidence