HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-6-nitro-1H-indole → 5-(1-benzyl-5-fluoro-3-indolyl)-5-(1-methyl-6-nitro-3-indolyl)-3,4-dichloro-2(5H)-furanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-6-nitro-1H-indole | HCID 10607359 | — |
| Reactant | 4-(1-Benzyl-5-fluoro-3-indolyl)-2,3-dichloro-4-oxo-2-butenoic acid | HCID 54289084 | — |
| Product | 5-(1-benzyl-5-fluoro-3-indolyl)-5-(1-methyl-6-nitro-3-indolyl)-3,4-dichloro-2(5H)-furanone | HCID 20442744 | — |
Reaction Steps
Following a procedure similar to that described above in part B of this example by using 4-(1-benzyl-5-fluoro-3-indolyl)-2,3-dichloro-4-oxo-2-butenoic acid instead of 4-(1,2-dimethyl-3-indolyl)-2,3-dichloro-4-oxo-2-butenoic acid and 1-methyl-6-nitroindole in place of 1,2-dimethylindole, there is obtained 5-(1-benzyl-5-fluoro-3-indolyl)-5-(1-methyl-6-nitro-3-indolyl)-3,4-dichloro-2(5H)-furanone (Formula V: R=C6H5CH2 ; R1 =R3 =H; R2 =CH3 ; Y=6-F; Y1 =6-NO2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04075224 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-0f45ac29a53c4827962ccf8801e5acec |
| Source note | uspto-grants-1978_02 |