1H-Indole, 1-ethyl-2-methyl- → HCID 20442778, compound

Participants

Reaction Steps

A mixture of 7.0 g (0.02 mole) of 4-(2-phenyl-3-indolyl)-2,3-dichloro-4-oxo-2-butenoic acid (prepared in part A above), 3.5 g (0.02 mole of 1-ethyl-2-methylindole and 200 ml of acetic anhydride was stirred at ambient temperature in an atmosphere of air for approximately seventeen hours. The pale blue solid that formed was collected by filtration and dried in vacuo at 60° C to obtain 5-(2-phenyl-3-indolyl)-5-(1-ethyl-2-methyl-3-indolyl)-3,4-dichloro-2(5H)-furanone (Formula V: R=Y=Y1 =H; R1 =C6H5 ; R2 =CH3CH2 ; R3 =CH3) as a tan-colored solid which started to sinter at 213° C and was completely melted at 225° C.

Provenance & Evidence