HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Thiophenecarboxylic acid, 3-(chlorosulfonyl)-, methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-(Methoxycarbonyl)thiophene-3-sulfonic acid | HCID 21431579 | — |
| Product | 2-Thiophenecarboxylic acid, 3-(chlorosulfonyl)-, methyl ester | HCID 2736733 | — |
Reaction Steps
7.4 g. of crude 3-sulfothiophene-2-carboxylic acid methyl ester are dissolved in 50 ml. of thionyl chloride and boiled to reflux for 16 hours. The mixture is then evaporated to dryness in vacuo and the remaining bright-yellow oil is brought to crystallization with petroleum ether. There is obtained 3-chlorosulfonylthiophene-2-carboxylic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04076709 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-a4e44558658d4a60b7cd5ca118e6b7a1 |
| Source note | uspto-grants-1978_02 |