HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formic Acid → Ethyl 7-(2-hydroxy-5-oxocyclopent-3-en-1-yl)heptanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | Hydroquinone | HCID 785 | — |
| Reactant | Sodium Formate | HCID 2723810 | — |
| Reactant | HCID 14142143 | HCID 14142143 | — |
| Solvent | 1,4-Dioxane--water (1/1) | HCID 21886435 | — |
| Product | Ethyl 7-(2-hydroxy-5-oxocyclopent-3-en-1-yl)heptanoate | HCID 22165421 | — |
Reaction Steps
A stirred mixture of 2.0g (7.87 mmol) of α-(6-carbethoxyhexyl)furfuryl alcohol (Example 4), 5.93 ml of 97% formic acid, 268 mg of sodium formate, 10 mg of hydroquinone, and 40 ml of 3:2 dioxane-water is stirred at reflux for 18 hr. The solution is cooled, saturated with salt, and extracted with ether. The extract is washed with brine, dried over magnesium sulfate, and concentrated to give an amber oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04076732 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-64bb7f9bac5d4e708434b8553e15d131 |
| Source note | uspto-grants-1978_02 |