Phenyl isocyanate → HCID 20366866, compound

HRID 616902Notes

Reaction equation

HRID 616902 reaction equation
[CH3:1][NH:2][CH:3]1[CH2:12][CH:11]2[N:6]([CH2:7][CH2:8][C:9]3[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=32)[CH2:5][CH2:4]1.[C:17]1([N:23]=[C:24]=[O:25])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:12]1[CH:11]2[N:6]([CH2:7][CH2:8][C:9]3[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=32)[CH2:5][CH2:4][CH:3]1[N:2]([CH3:1])[C:24]([NH:23][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:25]

Participants

3

Procedure

By a procedure analogous to that of Example 1, 2-methylamino-1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizine (J. Med. Chem., 1972, 15, 91) is reacted with phenyl isocyanate to give the title compound.

Sources & evidence

ORD record
ord-4a97e1b4695c4f90ba6a4fa20d30124a
Source dataset
uspto-grants-1978_02
Patent number
US04076820

Reaction notes

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