Phenyl isocyanate → HCID 86735507, compound

HRID 616905Notes

Reaction equation

HRID 616905 reaction equation
N[CH:2]1[CH2:11][CH:10]2[N:5]([CH2:6][CH2:7][C:8]3[CH:15]=[C:14]([Cl:16])[CH:13]=[CH:12][C:9]=32)[CH2:4][CH2:3]1.ClC1C=CC2C3[N:27](CCC=2C=1)CCC(=O)C3.[C:33]1([N:39]=[C:40]=[O:41])[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1>>[Cl:16][C:14]1[CH:13]=[CH:12][C:9]2[CH:10]3[N:5]([CH2:6][CH2:7][C:8]=2[CH:15]=1)[CH2:4][CH2:3][CH:2]([C:33]1([NH:39][C:40]([NH2:27])=[O:41])[CH:38]=[CH:37][CH:36]=[CH:35][CH2:34]1)[CH2:11]3

Participants

4

Reactant 3

HCID 7672Phenyl isocyanateHCID 20366875HCID 20366875, compoundHCID 20366881HCID 20366881, compound

Product 1

HCID 86735507HCID 86735507, compound

Procedure

2-Amino-9-chloro-1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizine [prepared from 9-chloro-1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizin-2-one (Neth.Appln. No. 6,508,468) by reduction of the oxime] is reacted with phenyl isocyanate by a procedure analogous to that of Example 1 to give the title compound.

Sources & evidence

ORD record
ord-118494444b9d4772b8bd660bab5d9a9c
Source dataset
uspto-grants-1978_02
Patent number
US04076820

Reaction notes

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