Methanesulfonyl chloride → HCID 20366879, compound

HRID 616906Notes

Reaction equation

HRID 616906 reaction equation
[NH2:1][CH:2]1[CH2:11][CH:10]2[N:5]([CH2:6][CH2:7][C:8]3[CH:15]=[CH:14][C:13]([CH3:16])=[CH:12][C:9]=32)[CH2:4][CH2:3]1.CC1C=CC2CCN3C(CC(=O)CC3)C=2C=1.[CH3:33][S:34](Cl)(=[O:36])=[O:35]>>[CH3:33][S:34]([NH:1][CH:2]1[CH2:11][CH:10]2[N:5]([CH2:6][CH2:7][C:8]3[CH:15]=[CH:14][C:13]([CH3:16])=[CH:12][C:9]=32)[CH2:4][CH2:3]1)(=[O:36])=[O:35]

Participants

4

Reactant 3

HCID 31297Methanesulfonyl chlorideHCID 20366862HCID 20366862, compoundHCID 20366876HCID 20366876, compound

Product 1

HCID 20366879HCID 20366879, compound

Procedure

2-Amino-1,3,4,6,7,11b-hexahydro-10-methyl-2H-benzo[a]quinolizine [prepared from 1,3,4,6,7,11b-hexahydro-10-methyl-2H-benzo[a]quinolizin-2-one (Neth.Appln. No. 6,508,468) by reduction of the oxime] is reacted with methane sulphonyl chloride by a process analogous to that of Example 7(a) to give the title compound.

Sources & evidence

ORD record
ord-f91679f33e7b42a5b8942dc4f81fc7c6
Source dataset
uspto-grants-1978_02
Patent number
US04076820

Reaction notes

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