m-Chloroperbenzoic acid → HCID 178502047, compound

Participants

Reaction Steps

To a mixture of 3.2 g of [5-[(cyclohexylmethyl)thio]-1H-benzimidazol-2-yl]carbamic acid, methyl ester in 120 ml CHCl3 and 120 ml HOAc at -20° C there is added a solution of 2.1 g of m-chloroperbenzoic acid. The resulting mixture is stirred and allowed to warm to room temperature. Stirring is continued for 5 hours and then CHCl3 is removed in vacuo. Water is added and the solution is neutralized with NaHCO3. The resulting solid is filtered off and crystallized from acetonitrile (1.5 g) to give the title compound, m.p. 272°-274° C.

Provenance & Evidence