反应详情

To a suspension of 4.6 g (0.019 mole) of 5,6-dihydro-5-oxopyrazolo[1,5-c]quinazoline-2-carbonyl chloride in 200 ml of pyridine under nitrogen is added, slowly in a dropwise fashion, a solution of 1.98 g (0.019 mole) of n-butanol. After stirring overnight at room temperature, the reaction mixture is filtered and the filtrate concentrated to a small volume and diluted with cold water. The title compound is filtered off and dried, m.p. 198°-200°.

1. additionis added, slowly in a dropwise fashion
2. filtrationthe reaction mixture is filtered
3. concentrationthe filtrate concentrated to a small volume
4. additiondiluted with cold water
5. filtrationThe title compound is filtered off
6. customdried