HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → HCID 20367026, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Methyl 4-(2-methoxy-2-oxoethyl)-β-methylbenzenepentanoate | HCID 54245713 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 20367026 | HCID 20367026 | — |
Reaction Steps
A solution of 20 g of potassium hydroxide in 40 cc of water is added to a solution of 19.3 g of 5-(4-carbomethoxymethylphenyl)-3-methylvaleric acid methyl ester in 200 cc of methanol and the mixture is heated at reflux for 2 hours. The solution is subsequently concentrated, diluted with water, acidified with 2 N hydrochloric acid and extracted with ether. The crude 5-(4-carboxymethylphenyl)-3-methylvaleric acid obtained after concentrating the ether extract, is recrystallized from ether/hexane. M.P. 100°-102°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04076838 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-ea91064128774b9c93a6e46ce1e5eee8 |
| Source note | uspto-grants-1978_02 |