Phosphorus pentachloride → HCID 53804381, compound

Participants

Reaction Steps

193 g of phosphorus pentachloride are added to a solution of 76.8 g of 2-methyl-4-(4-propionylphenyl)butyric acid methyl ester in one liter of anhydrous ether, and the mixture is stirred at room temperature for 16 hours and is subsequently heated at reflux for one hour. The mixture is slowly poured on ice, is stirred for one hour and extracted with ether. The 4-[4-(1-chloro-1-propenyl)phenyl]-2-methylbutyric acid methyl ester obtained after evaporating the ether extract, is distilled in a vacuum (bulb type). B.P. 160°-170° at 0.06 mm of Hg.

Provenance & Evidence