HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 6,7-Dimethoxy-4-(3,4-dimethoxyphenyl)-2-methylquinoline-3-carboxylic acid propyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Propyl acetoacetate | HCID 74507 | — |
| Reactant | 2-Amino-4,5,3',4'-tetramethoxybenzophenone | HCID 9926967 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 6,7-Dimethoxy-4-(3,4-dimethoxyphenyl)-2-methylquinoline-3-carboxylic acid propyl ester | HCID 21851159 | 79% |
Reaction Steps
Conc. sulfuric acid was added to a mixture of 2-amino-4,5,3',4'-tetramethoxybenzophenone, propyl acetoacetate and acetic acid. The resulting mixture was treated according to the same manner as that described in Reference example 1 to obtain propyl 6,7-dimethoxy-4-(3,4- dimethoxyphenyl)-2-methylquinoline-3-carboxylate (79%) which was recrystallized from ethyl acetate/isopropyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05948782 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-5af6e7af5c5149a899c8f1faae6e54af |
| Source note | uspto-grants-1999_09 |