Sodium Hydroxide → HCID 67585000, compound

HRID 617365Notes

Reaction equation

HRID 617365 reaction equation
[ClH:1].Cl.[CH3:3][N:4]1[CH2:8][CH2:7][CH2:6][C@H:5]1[CH2:9][O:10][C:11]1[CH:12]=[N:13][CH:14]=[C:15]([C:17]([O:19]CC)=[O:18])[CH:16]=1.[OH-].[Na+]>>[ClH:1].[ClH:1].[CH3:3][N:4]1[CH2:8][CH2:7][CH2:6][C@H:5]1[CH2:9][O:10][C:11]1[CH:12]=[N:13][CH:14]=[C:15]([C:17]([OH:19])=[O:18])[CH:16]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 131721356HCID 131721356, compound

Product 1

HCID 67585000HCID 67585000, compound

Procedure

A sample of the compound from Example 100 above is hydrolyzed with 1N NaOH according to standard methods. The product is purified by chromatography on silica gel and converted into the title compound by treatment with HCl in ether according to Example 14c.

Workup

  1. customThe product is purified by chromatography on silica gel

Sources & evidence

ORD record
ord-e990cf16b30c47028c4d293f32a11b64
Source dataset
uspto-grants-1999_09
Patent number
US05948793

Reaction notes

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