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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 617424Generated: October 30, 2026

Morpholine → 5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester

https://huagongshe.com/reaction/617424

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant5-Chlorocarbonyl-pyridine-2-carboxylic acid methyl esterHCID 15121177—
Product5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl esterHCID 20622307—

Reaction Steps

In step b, the acid chloride 11 is amidated with morpholine 12 by techniques and procedures well known and appreciated by one of ordinary skill in the art to give the corresponding 5-(morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester 13.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05948886
Source datasetuspto-grants-1999_09
ORD IDord-07b089f752ad4aefa9985ae850a70cc5
Source noteuspto-grants-1999_09