Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61743Generated: October 30, 2026

4-Cyclopentylpiperazin-2-one → 8-(4-Cyclopentyl-2-oxo-piperazin-1-yl)-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

https://huagongshe.com/reaction/61743

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Cyclopentylpiperazin-2-oneHCID 53415025—
ReactantTrifluoro-methanesulfonic acid 3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl esterHCID 86663817—
Product8-(4-Cyclopentyl-2-oxo-piperazin-1-yl)-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileHCID 66834296—

Reaction Steps

Under the same conditions as the method for synthesizing Compound B2-10, the title compound was prepared from Compound B1 and 4-cyclopentylpiperazin-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440922B2
Source datasetuspto-grants-2016_09
ORD IDord-82dcc16ec971476da365b6c6c5100b4f
Source noteuspto-grants-2016_09