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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61744Generated: October 25, 2026

4-Morpholinopiperidine → 6,6-Dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

https://huagongshe.com/reaction/61744

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MorpholinopiperidineHCID 795724—
ReactantTrifluoro-methanesulfonic acid 3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl esterHCID 86663817—
Product6,6-Dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileHCID 57396463—

Reaction Steps

Under the same conditions as the method for synthesizing Compound B2-1, the title compound was prepared from Compound B1 and 4-piperidin-4-yl morpholine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440922B2
Source datasetuspto-grants-2016_09
ORD IDord-fa4a60b1a7f44dc3962e20135e802523
Source noteuspto-grants-2016_09