4-Fluorobenzylamine → 2,4-Dichloro-5-methylthieno(2,3-d)pyrimidine

Participants

Role	Name	HCID	Charge
Reactant	4-Fluorobenzylamine	HCID 67326	—
Reactant	2,4-Dichloro-6-methylthieno[2,3-D]pyrimidine	HCID 11106847	—
Product	2,4-Dichloro-5-methylthieno(2,3-d)pyrimidine	HCID 12225299	—
Product	2-Chloro-6-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine	HCID 18460383	—

Reaction Steps

Following the procedure of Example 1, the reaction of 4-fluorobenzylamine with 2,4-dichloro-6-methyl-thieno-[2,3-d]-pyrimidine yields 2-chloro-6-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine with 2,4-dichloro-5-methyl-thieno-[2,3-d]-pyrimidine yields 2-chloro-5-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05948911
Source dataset	uspto-grants-1999_09
ORD ID	ord-13999e87471a476e833ed7611f8a7728
Source note	uspto-grants-1999_09