Benzenemethanamine, 3,4-dichloro- → 2-Chloro-5-methyl-4-(3,4-dichlorobenzylamino)-thieno-[2,3-d]-pyrimidine

HRID 617488Notes

Reaction equation

HRID 617488 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH2:5][NH2:6].[Cl:11][C:12]1[N:13]=[C:14](Cl)[C:15]2[C:20]([CH3:21])=[CH:19][S:18][C:16]=2[N:17]=1>>[Cl:11][C:12]1[N:13]=[C:14]([NH:6][CH2:5][C:4]2[CH:7]=[CH:8][C:9]([Cl:10])=[C:2]([Cl:1])[CH:3]=2)[C:15]2[C:20]([CH3:21])=[CH:19][S:18][C:16]=2[N:17]=1

Participants

3

Reactant 2

HCID 1608Benzenemethanamine, 3,4-dichloro-HCID 122252992,4-Dichloro-5-methylthieno(2,3-d)pyrimidine

Product 1

HCID 184604212-Chloro-5-methyl-4-(3,4-dichlorobenzylamino)-thieno-[2,3-d]-pyrimidine

Procedure

Following the procedure of Example 1, the reaction of 3,4-dichlorobenzylamine with 2,4-dichloro-5-methyl-thieno-[2,3-d]-pyrimidine yields 2-chloro-5-methyl-4-(3,4-dichlorobenzylamino)-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-815e4474e9474061bf6091e15786f506
Source dataset
uspto-grants-1999_09
Patent number
US05948911

Reaction notes

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