Benzenemethanamine, 3,4-dichloro- → HCID 23289589, compound

HRID 617549Notes

Reaction equation

HRID 617549 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH2:5][NH2:6].[CH3:11][O:12][C:13](=[O:32])[C:14]1[CH:19]=[CH:18][C:17]([C:20]2[N:21]=[C:22](Cl)[C:23]3[C:28]([CH3:29])=[C:27]([CH3:30])[S:26][C:24]=3[N:25]=2)=[CH:16][CH:15]=1>>[CH3:11][O:12][C:13](=[O:32])[C:14]1[CH:15]=[CH:16][C:17]([C:20]2[N:21]=[C:22]([NH:6][CH2:5][C:4]3[CH:7]=[CH:8][C:9]([Cl:10])=[C:2]([Cl:1])[CH:3]=3)[C:23]3[C:28]([CH3:29])=[C:27]([CH3:30])[S:26][C:24]=3[N:25]=2)=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 1608Benzenemethanamine, 3,4-dichloro-HCID 23289650HCID 23289650, compound

Product 1

HCID 23289589HCID 23289589, compound

Procedure

The reaction procedure as above wherein 3,4-dichlorobenzylamine is reacted with 4-(4-chloro-5,6-dimethyl-thieno-[2,3-d]-pyrimidin-2-yl)-benzoic acid methylester yields 4-[4-(3,4-dichlorobenzylamino)-5,6-dimethyl-thieno-[2,3-d]-pyrimidin-2-yl]-benzoic acid methylester.

Sources & evidence

ORD record
ord-e993fe81734541b9b941a815b11eb70f
Source dataset
uspto-grants-1999_09
Patent number
US05948911

Reaction notes

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