Benzenemethanamine, 3,4-dichloro- → 4-[4-(3,4-Dichlorobenzylamino)-6-trifluoromethyl-thieno-[2,3-d]-pyrimidin-2-yl]-benzoic acid methylester

HRID 617550노트

반응식

HRID 617550 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH2:5][NH2:6].[CH3:11][O:12][C:13](=[O:34])[C:14]1[CH:19]=[CH:18][C:17]([C:20]2[N:21]=[C:22](Cl)[C:23]3[CH:28]=[C:27]([C:29]([F:32])([F:31])[F:30])[S:26][C:24]=3[N:25]=2)=[CH:16][CH:15]=1>>[CH3:11][O:12][C:13](=[O:34])[C:14]1[CH:19]=[CH:18][C:17]([C:20]2[N:21]=[C:22]([NH:6][CH2:5][C:4]3[CH:7]=[CH:8][C:9]([Cl:10])=[C:2]([Cl:1])[CH:3]=3)[C:23]3[CH:28]=[C:27]([C:29]([F:32])([F:31])[F:30])[S:26][C:24]=3[N:25]=2)=[CH:16][CH:15]=1

참가 물질

3

반응물 2

HCID 1608Benzenemethanamine, 3,4-dichloro-HCID 232894044-(4-Chloro-6-trifluoromethyl-thieno-[2,3-d]-pyrimidin-2-yl)-benzoic acid methylester

생성물 1

HCID 232895364-[4-(3,4-Dichlorobenzylamino)-6-trifluoromethyl-thieno-[2,3-d]-pyrimidin-2-yl]-benzoic acid methylester

실험 절차

The reaction procedure as above wherein 3,4-dichlorobenzylamine is reacted with 4-(4-chloro-6-trifluoromethyl-thieno-[2,3-d]-pyrimidin-2-yl)-benzoic acid methylester yields 4-[4-(3,4-dichlorobenzylamino)-6-trifluoromethyl-thieno-[2,3-d]-pyrimidin-2-yl]-benzoic acid methylester.

출처 및 근거

ORD 기록
ord-1eb440ab978d482ca1102a9f5efcc15d
출처 데이터셋
uspto-grants-1999_09
특허 번호
US05948911

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