3-Nitrobenzylamine → HCID 23289514, compound

HRID 617553Notes

Reaction equation

[N+:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH2:7][NH2:8])([O-:3])=[O:2].[CH3:12][O:13][C:14](=[O:35])[C:15]1[CH:20]=[CH:19][C:18]([C:21]2[N:22]=[C:23](Cl)[C:24]3[C:29]4[CH2:30][CH2:31][CH2:32][CH2:33][C:28]=4[S:27][C:25]=3[N:26]=2)=[CH:17][CH:16]=1>>[CH3:12][O:13][C:14](=[O:35])[C:15]1[CH:16]=[CH:17][C:18]([C:21]2[N:22]=[C:23]([NH:8][CH2:7][C:6]3[CH:9]=[CH:10][CH:11]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=3)[C:24]3[C:29]4[CH2:30][CH2:31][CH2:32][CH2:33][C:28]=4[S:27][C:25]=3[N:26]=2)=[CH:19][CH:20]=1

Participants

Reactant 2

HCID 1227223-Nitrobenzylamine

HCID 23289655HCID 23289655, compound

Product 1

HCID 23289514HCID 23289514, compound

Procedure

The reaction procedure as above wherein 3-nitrobenzylamine is reacted with 4-(4-chloro-5,6,7,8,-tetrahydro-[1]-benzothieno-[2,3-d]-pyrimidin-2-yl)-benzoic acid methylester yields 4-[4-(3-nitrobenzylamino)-5,6,7,8-tetrahydro-[1]-benzothieno-[2,3-d]-pyrimidin-2-yl]-benzoic acid methylester.

Sources & evidence

ORD record: ord-6ee348bae72a4a699c5f7e6232a1feeb
Source dataset: uspto-grants-1999_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05948911

Reaction notes

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