2-(Methylsulfonyl)ethanamine → 3-Cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-carboxylic acid (2-methanesulfonyl-ethyl)-amide
Reaction equation
[C:1]([C:3]1[CH:15]=[C:14]2[C:6]([C:7]3[C:8](=[O:25])[C:9]4[CH:21]=[CH:20][C:19]([C:22]([OH:24])=O)=[CH:18][C:10]=4[C:11]([CH3:17])([CH3:16])[C:12]=3[NH:13]2)=[CH:5][CH:4]=1)#[N:2].[CH3:26][S:27]([CH2:30][CH2:31][NH2:32])(=[O:29])=[O:28]>>[CH3:26][S:27]([CH2:30][CH2:31][NH:32][C:22]([C:19]1[CH:20]=[CH:21][C:9]2[C:8](=[O:25])[C:7]3[C:6]4[C:14](=[CH:15][C:3]([C:1]#[N:2])=[CH:4][CH:5]=4)[NH:13][C:12]=3[C:11]([CH3:16])([CH3:17])[C:10]=2[CH:18]=1)=[O:24])(=[O:29])=[O:28]Participants
3
Procedure
Under the same conditions as the method for synthesizing Compound B3-15, the title compound was prepared from Compound B2-28 and 2-methanesulfonylethylamine.
Sources & evidence
- ORD record
- ord-63174691f75e4982977fb401c08ec2a8
- Source dataset
- uspto-grants-2016_09
- Patent number
- US09440922B2
Reaction notes
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