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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61766Generated: October 25, 2026

(2R)-3-aminopropane-1,2-diol → 3-Cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-carboxylic acid ((R)-2,3-dihydroxy-propyl)-amide

https://huagongshe.com/reaction/61766

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2R)-3-aminopropane-1,2-diolHCID 6994409—
Reactant3-Cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-carboxylic acidHCID 66834398—
Product3-Cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-carboxylic acid ((R)-2,3-dihydroxy-propyl)-amideHCID 66834090—

Reaction Steps

Under the same conditions as the method for synthesizing Compound B3-15, the title compound was prepared from Compound B2-28 and (R)-(+)-3-amino-1,2-propanediol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440922B2
Source datasetuspto-grants-2016_09
ORD IDord-c1d6f98bd5e441ac9c4e5c10b3149e1f
Source noteuspto-grants-2016_09