Acetaldehyde → Pyridine

HRID 617686Notes

Reaction equation

HRID 617686 reaction equation
[CH:1](=O)[CH3:2].C=O.[N:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>>[N:6]1[CH:7]=[CH:8][CH:9]=[CH:10][C:1]=1[CH3:2].[N:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

Participants

5

Reactant 3

HCID 177AcetaldehydeHCID 712FormaldehydeHCID 1049Pyridine

Product 2

HCID 1049PyridineYield 47%HCID 79752-MethylpyridineYield 17%

Procedure

Specifically, Examples of the above-described U.S. Pat. No. 4,861,894 describe that the pyridine bases are synthesized using acetaldehyde and formaldehyde as starting materials to obtain pyridine yield of 47% and picoline yield of 17% (total yield of 61%). Furthermore, Japanese Patent Publication Kokoku No. 92368/1994 [Japanese Patent Publication Kokai No. 181256/1987] and Japanese Patent Publication Kokoku No. 92369/1994 [Japanese Patent Publication Kokai No. 139168/1988] describe processes in which there are employed zeolites in or on to which Tl, Co, and Pb compounds are carried.

Workup

  1. customare synthesized

Sources & evidence

ORD record
ord-5e410a02f1984a108fd19c44e23505f8
Source dataset
uspto-grants-1999_09
Patent number
US05952258

Reaction notes

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