2-Chloropyridine → HCID 15177822, compound

HRID 617748Notes

Reaction equation

HRID 617748 reaction equation
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[N:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH2:14][CH:15]2[CH:24]([OH:25])[C:23]3[C:18](=[CH:19][CH:20]=[C:21]([OH:26])[CH:22]=3)[O:17][CH2:16]2)[CH:9]=1>>[N:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH2:14][C@H:15]2[C@@H:24]([OH:25])[C:23]3[C:18](=[CH:19][CH:20]=[C:21]([O:26][C:2]4[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=4)[CH:22]=3)[O:17][CH2:16]2)[CH:9]=1

Participants

3

Reactant 2

HCID 79772-ChloropyridineHCID 15181191HCID 15181191, compound

Product 1

HCID 15177822HCID 15177822, compound

Procedure

By the method of Example 1, 2-chloropyridine and 3-(3-pyridylmethyl)-4,6-chromandiol were converted to present title product in like yield; mp 67-68° C.; IR(CHCl3) 1598; 1491 cm-1.

Sources & evidence

ORD record
ord-f85b1f6baa0e449fb1a545db71ea1c71
Source dataset
uspto-grants-1999_09
Patent number
US05952326

Reaction notes

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