2-Chloroquinoline → HCID 67559724, compound

HRID 617749Notes

Reaction equation

HRID 617749 reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[N:12]1[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH:19]2[CH:28]([OH:29])[C:27]3[C:22](=[CH:23][CH:24]=[C:25]([OH:30])[CH:26]=3)[O:21][CH2:20]2)[CH:13]=1>>[N:12]1[CH:17]=[CH:16][CH:15]=[C:14]([O:18][C@H:19]2[C@@H:28]([OH:29])[C:27]3[C:22](=[CH:23][CH:24]=[C:25]([O:30][C:2]4[CH:11]=[CH:10][C:9]5[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=5)[N:3]=4)[CH:26]=3)[O:21][CH2:20]2)[CH:13]=1

Participants

3

Reactant 2

HCID 119282-ChloroquinolineHCID 19600666HCID 19600666, compound

Product 1

HCID 67559724HCID 67559724, compound

Procedure

By the method of Example 1, 2-chloroquinoline and 3-(3-pyridyloxy)-4,6-chromandiol (EP appln. 312,295) were converted to present title product in like yield; mp 112-114° C.; IR (CHCl3) 3563, 1620, 1603 cm-1.

Sources & evidence

ORD record
ord-de5c8bc58b4b47289258527333c7c044
Source dataset
uspto-grants-1999_09
Patent number
US05952326

Reaction notes

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