Diethylamine → HCID 18391841, compound

Participants

Reaction Steps

According to the procedure given in Example 21, Step D, 86 mg (0.18 mmol) of 3,3-diethyl-1-[(R)-α-(allyl)-4-(methyl)benzylaminocarbonyl]-4-(S)-[4-(1-(RS)-(hydroxy)-2-methoxyethyl) phenoxy]azetidin-2-one, 98 mg (0.23 mmol) of triphenylphosphine dibromide and ca. 0.3 mL of diethylamine gave after purification on 15 gm of silica eluting with 500 mL of 98:2 methylene chloride: methanol then 200 mL of 97.5:2.5 methylene chloride: methanol 44 mg (46%) of an oil.

Provenance & Evidence