Hydrochloric Acid → HCID 21849537, compound

Participants

Reaction Steps

2-Acetamido-1,3-diacetoxy-2-docosylpropane (1.5 g) was dissolved in 40 ml of methanol and 9.6 ml of a 1 N aqueous sodium hydroxide solution was added thereto. The mixture was refluxed under heating for 6 hours., The mixture was neutralized with a 1 N aqueous hydrochloric acid solution and concentrated under reduced pressure. The concentrate was washed with water and ethyl acetate:hexane=1:1 in order to give 846 mg of 2-amino-2-docosyl-1,3-propanediol hydrochloride.

Provenance & Evidence