関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Carbon tetrabromide | HCID 11205 | — |
| 反応物 | Triphenylphosphine | HCID 11776 | — |
| 反応物 | Dodecanediol monotetrahydropyranyl ether | HCID 21849359 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 2H-Pyran, 2-[(12-bromododecyl)oxy]tetrahydro- | HCID 11078592 | 41.9% |
反応手順
The above-mentioned dodecanediol monotetrahydropyranyl ether (7.882 g) and 11.437 g of carbon tetrabromide were dissolved in 78 ml of dichloromethane. Triphenylphosphine (10.843 g) was added thereto under ice-cooling and the mixture was stirred at 0° C. for 5 minutes. The solvent was distilled away under reduced pressure and the residue was purified by silica gel column chromatography to give 4.029 g of 1-bromo-12-tetrahydropyranyloxydodecane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05952316 |
|---|
| 出典データセット | uspto-grants-1999_09 |
|---|
| ORD ID | ord-e94eee4e3bfa40f59b0a2b100106af41 |
|---|
| 出典メモ | uspto-grants-1999_09 |
|---|
