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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 617934Generated: October 25, 2026

6-(2,6-Dichlorophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine → 6-(2,6-dichlorophenyl)-2-N-[4-(4-methylpiperazin-1-yl)butyl]pyrido[2,3-d]pyrimidine-2,7-diamine

https://huagongshe.com/reaction/617934

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(2,6-Dichlorophenyl)pyrido[2,3-d]pyrimidine-2,7-diamineHCID 5328113—
Reactant4-(4-Methylpiperazin-1-yl)butan-1-amineHCID 6484192—
Product6-(2,6-dichlorophenyl)-2-N-[4-(4-methylpiperazin-1-yl)butyl]pyrido[2,3-d]pyrimidine-2,7-diamineHCID 5328150—

Reaction Steps

Following the procedure of Example 20, 2.0 g of 2,7-diamino-6-(2,6-dichlorophenyl)-pyrido[2,3-d]-pyrimidine from Example 1 was reacted with 15 mL of 1-(4-aminobutyl)-4-methyl-piperazine to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05952342
Source datasetuspto-grants-1999_09
ORD IDord-451d029a3748432aafe11c3059dd32c8
Source noteuspto-grants-1999_09