Benzeneacetonitrile, 2,3-dichloro- → 6-(2,3-Dichlorophenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine

HRID 617967Notes

Reaction equation

HRID 617967 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:9][C:10]#[N:11].[NH2:12][C:13]1[N:18]=[C:17]([NH2:19])[C:16]([CH:20]=O)=[CH:15][N:14]=1>>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[C:10]([NH2:11])=[N:19][C:17]2[N:18]=[C:13]([NH2:12])[N:14]=[CH:15][C:16]=2[CH:20]=1

Participants

3

Reactant 2

HCID 229020Benzeneacetonitrile, 2,3-dichloro-HCID 3091762,4-Diaminopyrimidine-5-carbaldehyde

Product 1

HCID 218500486-(2,3-Dichlorophenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine

Procedure

Following the procedure of Example 1, 2,3-dichlorophenylacetonitrile was reacted with 2,4-diamino-5-pyrimidinecarboxaldehyde to give the title compound; mp 366-369° C. (dec).

Sources & evidence

ORD record
ord-9f3d564569c243c99ca8197a56923966
Source dataset
uspto-grants-1999_09
Patent number
US05952342

Reaction notes

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