1-Bromo-2-methylpropane → HCID 15432606, compound
Reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3](/[CH:10]=[CH:11]/[C:12]([C:14]2[CH:19]=[C:18]([O:20][CH3:21])[C:17]([O:22][CH3:23])=[C:16]([O:24][CH3:25])[CH:15]=2)=[O:13])=[CH:2]1.[CH2:26](Br)[CH:27]([CH3:29])[CH3:28]>>[CH2:26]([N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3](/[CH:10]=[CH:11]/[C:12]([C:14]2[CH:19]=[C:18]([O:20][CH3:21])[C:17]([O:22][CH3:23])=[C:16]([O:24][CH3:25])[CH:15]=2)=[O:13])=[CH:2]1)[CH:27]([CH3:29])[CH3:28]Participants
3
Procedure
Substantially the same procedure as in Example 3 was repeated using Compound 1 (1.69 g) obtained in Example 1 and isobutyl bromide (0.82 ml) to give Compound 5 (1.32 g).
Sources & evidence
- ORD record
- ord-2094ec45397343798dd96e17e5555288
- Source dataset
- uspto-grants-1999_09
- Patent number
- US05952355
Reaction notes
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