Acetic Anhydride → HCID 15432607, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of Compound 1 (1.69 g) obtained in Example 1, acetic anhydride (5.04 g) and pyridine (5.6 ml) was heated at 100° C. for 12 hours. The reaction solution was subjected to partitioning between chloroform and a 10% aqueous solution of citric acid. The organic layer was concentrated under reduced pressure, and the residue was recrystallized from ethyl acetate to give Compound 6 (1.32 g).

Provenance & Evidence