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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 618107Generated: October 30, 2026

Methanol → HCID 21850241, compound

https://huagongshe.com/reaction/618107

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantHCID 21850191HCID 21850191—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
ProductHCID 21850241HCID 21850241100.1%

Reaction Steps

5-Benzyloxy-6-methoxyindole-3-carboxaldehyde (0.75 g) was suspended in a mixed solvent of methanol (60 ml) and ethyl acetate (20 ml), and 10% palladium on carbon (85 mg) was added thereto, followed by stirring at room temperature for one hour under an atmosphere of hydrogen. The catalyst was filtered off, and the filtrate was concentrated under reduced pressure to give 5-hydroxy-6-methoxyindole-3-carboxaldehyde (0.51 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05952355
Source datasetuspto-grants-1999_09
ORD IDord-76da15c2073b410390a454915c90d713
Source noteuspto-grants-1999_09