HuagongsheHuagongshe Chemistry Print Report · For research reference only
3',4',5'-Trimethoxyacetophenone → (E)-3-(6-Chloroindol-3-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3',4',5'-Trimethoxyacetophenone | HCID 14345 | — |
| Reactant | 6-Chloro-1H-indole-3-carboxaldehyde | HCID 12614669 | — |
| Product | (E)-3-(6-Chloroindol-3-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-one | HCID 21850251 | 69.2% |
Reaction Steps
Substantially the same procedure as in Example 1 was repeated using 3',4',5'-trimethoxyacetophenone (2.1 g) and 6-chloroindole-3-carboxaldehyde (1.8 g) except that the obtained product was recrystallized from ethyl acetate, to give Compound 42 (2.57 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05952355 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-dbec2b02c2eb4bf0b7f109ff3d2ef1a6 |
| Source note | uspto-grants-1999_09 |