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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 618116Generated: October 25, 2026

3',4',5'-Trimethoxyacetophenone → (E)-3-(7-Nitroindol-3-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-one

https://huagongshe.com/reaction/618116

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3',4',5'-TrimethoxyacetophenoneHCID 14345—
Reactant7-nitro-1H-indole-3-carbaldehydeHCID 2762438—
Product(E)-3-(7-Nitroindol-3-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-oneHCID 2185025944.2%

Reaction Steps

Substantially the same procedure as in Example 1 was repeated using 3',4',5'-trimethoxyacetophenone (630 mg) and 7-nitroindole-3-carboxaldehyde (552 mg) to give Compound 44 (491 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05952355
Source datasetuspto-grants-1999_09
ORD IDord-a4f5aa8b8b3f4bf0bca0312cecc673f7
Source noteuspto-grants-1999_09