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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 618117Generated: October 30, 2026

3',4',5'-Trimethoxyacetophenone → (E)-3-(7-Methoxyindol-3-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-one

https://huagongshe.com/reaction/618117

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3',4',5'-TrimethoxyacetophenoneHCID 14345—
Reactant7-Methoxy-3-indolecarboxaldehydeHCID 4141218—
Product(E)-3-(7-Methoxyindol-3-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-oneHCID 2185026848.3%

Reaction Steps

Substantially the same procedure as in Example 39 was repeated using 3',4',5'-trimethoxyacetophenone (1.74 g) and 7-methoxyindole-3-carboxaldehyde (1.45 g) to give Compound 46 (1.47 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05952355
Source datasetuspto-grants-1999_09
ORD IDord-8a91c4d059e34217b702efa267acaf87
Source noteuspto-grants-1999_09