3-Pyridinecarbonyl chloride, hydrochloride (1:1) → HCID 21850284, compound

HRID 618121Notes

Reaction equation

HRID 618121 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3](/[CH:10]=[CH:11]/[C:12]([C:14]2[CH:19]=[C:18]([O:20][CH3:21])[C:17]([O:22][CH3:23])=[C:16]([O:24][CH3:25])[CH:15]=2)=[O:13])=[CH:2]1.Cl.[C:27](Cl)(=[O:34])[C:28]1[CH:33]=[CH:32][CH:31]=[N:30][CH:29]=1>>[C:27]([N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3](/[CH:10]=[CH:11]/[C:12]([C:14]2[CH:19]=[C:18]([O:20][CH3:21])[C:17]([O:22][CH3:23])=[C:16]([O:24][CH3:25])[CH:15]=2)=[O:13])=[CH:2]1)(=[O:34])[C:28]1[CH:33]=[CH:32][CH:31]=[N:30][CH:29]=1

Participants

3

Reactant 2

HCID 884383-Pyridinecarbonyl chloride, hydrochloride (1:1)HCID 9927763170488-48-9

Product 1

HCID 21850284HCID 21850284, compoundYield 19.7%

Procedure

Substantially the same procedure as in Example 59 was repeated using Compound 1 (1.43 g) obtained in Example 1 and nicotinoyl chloride hydrochloride (1.51 g) to give Compound 60 (0.37 g).

Sources & evidence

ORD record
ord-ed96d0b6b0c74cbea76a867627ec0e3e
Source dataset
uspto-grants-1999_09
Patent number
US05952355

Reaction notes

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