HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Pyridinebutanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 4-(Pyridin-4-yl)butanoate | HCID 12114953 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Pyridinebutanoic acid | HCID 3159625 | — |
Reaction Steps
A solution of ester 10-4 (10.0 g, 56 mmol), 1N NaOH (84 ml, 84 mmole) and CH3OH (200 ml) was stiffed at ambient temperature for 1.0 h. Concentrated HCl (7.0 ml, 84 mmol) was added followed by concentration. The residue was dissolved in CHCl3, dried (MgSO4) and concentrated to give acid 10-5 as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05952306 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-b47adac019eb4475a9b353aedcb8d9c1 |
| Source note | uspto-grants-1999_09 |