HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Bromide → 4-(Bromomethyl)-1-methyl-2-nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Bromide | HCID 82050 | — |
| Reactant | 4-(Chloromethyl)-2-nitrotoluene | HCID 597730 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 4-(Bromomethyl)-1-methyl-2-nitrobenzene | HCID 12623674 | 85.5% |
Reaction Steps
4-Chloromethyl-1-methyl-2-nitro-benzene (5 g) was dissolved in 50 ml of acetone and 23.4 g of lithium bromide was added. The reaction mixture was heated at reflux for 18 hr. The solvent was evaporated off and the residue was tritrated with hexane to give 5.3 g of 4-bromomethyl-1-methyl-2-nitro-benzene as a tan solid. ##STR109##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05952362 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-773fee99717c4e479dc308d5aca10c38 |
| Source note | uspto-grants-1999_09 |